Collaborative case studies


LUMC, CHDR, LACR and TNO have a long-standing collaboration on different aspect of healthy and diseased skin. Our collaboration has led to multiple case studies exploring various aspects of skin health and disease. These studies demonstrate the added value of combining clinical, pharmacological, and technological expertise.

Atopic dermatitis: A combined approach of non-invasive monitoring and repair

LACDR-CHDR-LUMC

Combine diagnosis and repair of skin barrier properties to develop group-targetted therapy of AD patients.

Mimicking the in vivo skin barrier function in human skin equivalents

LACDR-LUMC

Generate a novel reproducible human skin equivalent (HSE) by mimicking all features for atopic dermatitis skin as closely as possible by establishing optimal culture conditions

Development of an atopic eczema human skin equivalent as a tool for screening purposes

LACDR-LUMC

Generate a novel and reproducible human skin equivalent (HSE) mimicking characteristics of atopic dermatitis skin by establishing optimal culture conditions

Deep phenotyping psoriasis

LACDR-CHDR-ErasmusMC-TNO

Elucidate novel disease characteristics and biomarkers and understand pathogenesis in greater detail function.

Deep phenotyping seborrheic dermatitis patients

LACDR-LUMC-CHDR-ErasmusMC-TNO

Elucidate novel disease characteristics and biomarkers. Understand pathogenesis in respect to inflammation vs. Malassezia vs. microbiome. Unravel skin barrier function and lipids in-depth

Wound healing in healthy volunteers

LACDR-LUMC-CHDR–ErasmusMC

Deep phenotype novel disease characteristics and biomarkers.

Deep phenotyping mycosis fungoides (cutaneous T cell lymphoma)

LACDR-LUMC-CHDR-TNO

Elucidate novel disease characteristics and biomarkers and understand pathogenesis in greater detail.


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If our case studies resonate with your ambitions, let’s explore how we can create impact together. We’re always open to new collaborations that accelerate clinical innovation and deliver measurable outcomes.

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